LrgpV1, Main, Exploration, bibRecord, 001835

Growth mechanisms in melt agglomeration in high shear mixers

Identifieur interne : 001835 ( Main/Exploration ); précédent : 001834; suivant : 001836

Growth mechanisms in melt agglomeration in high shear mixers

Auteurs : Torben Sch Fer [Danemark]

Source :

Powder Technology [ 0032-5910 ] ; 2001.

RBID : ISTEX:0A66E48C7BB2A2E3A49F7AB8EB59606F969FD515

Descripteurs français

Wicri :
- topic : Lactose.

English descriptors

KwdEn :
- Acta pharm, Agglomerate, Agglomerate formation, Agglomerate growth, Agglomerate growth mechanisms, Agglomerate size distribution, Agglomerate strength, Agglomeration, Agglomeration experiments, Agglomeration process, Anhydrous, Anhydrous dicalcium phosphate, Anhydrous lactose, Binder, Binder distribution, Binder viscosity, Breakage, Chem, Coalescence, Corn starch, Deformability, Densification, Distribution mechanism, Droplet, Granule, Granule size, High impeller speed, High shear mixer, High shear mixers, High viscosity, Higher impeller speed, Higher porosity, Higher viscosity, Holm, Immersion mechanism, Impeller, Impeller speed, Intragranular, Intragranular porosity, Kristensen, Lactose, Lactose monohydrate, Liquid saturation, Loose structure, Lower viscosity, Mass ratio, Meltable, Meltable binder, Mixer, Mixer torque rheometer, Molten binder, Monohydrate, Nucleation phase, Other hand, Particle shape, Particle size, Pelletization, Pelletization process, Pharm, Porosity, Powder technol, Powder technology, Primary particles, Resistivity, Saturation, Shearing forces, Size distribution, Small particle size, Solid binder, Solid particles, Static voltage, Stearic, Stearic acid, Technol, True density, Uncontrollable agglomerate growth, Wider size distribution.
Teeft :
- Acta pharm, Agglomerate, Agglomerate formation, Agglomerate growth, Agglomerate growth mechanisms, Agglomerate size distribution, Agglomerate strength, Agglomeration, Agglomeration experiments, Agglomeration process, Anhydrous, Anhydrous dicalcium phosphate, Anhydrous lactose, Binder, Binder distribution, Binder viscosity, Breakage, Chem, Coalescence, Corn starch, Deformability, Densification, Distribution mechanism, Droplet, Granule, Granule size, High impeller speed, High shear mixer, High shear mixers, High viscosity, Higher impeller speed, Higher porosity, Higher viscosity, Holm, Immersion mechanism, Impeller, Impeller speed, Intragranular, Intragranular porosity, Kristensen, Lactose, Lactose monohydrate, Liquid saturation, Loose structure, Lower viscosity, Mass ratio, Meltable, Meltable binder, Mixer, Mixer torque rheometer, Molten binder, Monohydrate, Nucleation phase, Other hand, Particle shape, Particle size, Pelletization, Pelletization process, Pharm, Porosity, Powder technol, Powder technology, Primary particles, Resistivity, Saturation, Shearing forces, Size distribution, Small particle size, Solid binder, Solid particles, Static voltage, Stearic, Stearic acid, Technol, True density, Uncontrollable agglomerate growth, Wider size distribution.

Abstract

Abstract: This paper presents a review of factors affecting the agglomerate formation and growth mechanisms in melt agglomeration in high shear mixers. The agglomerate formation occurs either by distribution or immersion or by a combination of both mechanisms. Distribution is promoted by a low binder viscosity, by a high impeller speed, and by a small binder particle size. Effects of the liquid saturation of the agglomerates, impeller speed, particle properties, binder viscosity, and electrostatic charging on the subsequent agglomerate growth are discussed, and experimental results are presented. The agglomerate growth becomes controlled by the balance between the agglomerate strength and the shearing forces. If the agglomerate strength is sufficiently high to resist the shearing forces of the rotating impeller, the dominant agglomerate growth mechanism will be coalescence. The shearing forces will give rise to breakage if the agglomerate strength is too low, and then agglomerate growth will occur by a simultaneous buildup and breakdown of agglomerates, possibly combined with growth by layering of fragments upon larger agglomerates. Provided that the liquid saturation is sufficiently high, a higher agglomerate strength is primarily caused by a higher binder viscosity, a smaller particle size, an irregular particle shape, and by densification of the agglomerates.

Url:

https://api.istex.fr/document/0A66E48C7BB2A2E3A49F7AB8EB59606F969FD515/fulltext/pdf

DOI: 10.1016/S0032-5910(01)00315-1

Affiliations:

Danemark

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Le document en format XML

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<term>Agglomerate formation</term>
<term>Agglomerate growth</term>
<term>Agglomerate growth mechanisms</term>
<term>Agglomerate size distribution</term>
<term>Agglomerate strength</term>
<term>Agglomeration</term>
<term>Agglomeration experiments</term>
<term>Agglomeration process</term>
<term>Anhydrous</term>
<term>Anhydrous dicalcium phosphate</term>
<term>Anhydrous lactose</term>
<term>Binder</term>
<term>Binder distribution</term>
<term>Binder viscosity</term>
<term>Breakage</term>
<term>Chem</term>
<term>Coalescence</term>
<term>Corn starch</term>
<term>Deformability</term>
<term>Densification</term>
<term>Distribution mechanism</term>
<term>Droplet</term>
<term>Granule</term>
<term>Granule size</term>
<term>High impeller speed</term>
<term>High shear mixer</term>
<term>High shear mixers</term>
<term>High viscosity</term>
<term>Higher impeller speed</term>
<term>Higher porosity</term>
<term>Higher viscosity</term>
<term>Holm</term>
<term>Immersion mechanism</term>
<term>Impeller</term>
<term>Impeller speed</term>
<term>Intragranular</term>
<term>Intragranular porosity</term>
<term>Kristensen</term>
<term>Lactose</term>
<term>Lactose monohydrate</term>
<term>Liquid saturation</term>
<term>Loose structure</term>
<term>Lower viscosity</term>
<term>Mass ratio</term>
<term>Meltable</term>
<term>Meltable binder</term>
<term>Mixer</term>
<term>Mixer torque rheometer</term>
<term>Molten binder</term>
<term>Monohydrate</term>
<term>Nucleation phase</term>
<term>Other hand</term>
<term>Particle shape</term>
<term>Particle size</term>
<term>Pelletization</term>
<term>Pelletization process</term>
<term>Pharm</term>
<term>Porosity</term>
<term>Powder technol</term>
<term>Powder technology</term>
<term>Primary particles</term>
<term>Resistivity</term>
<term>Saturation</term>
<term>Shearing forces</term>
<term>Size distribution</term>
<term>Small particle size</term>
<term>Solid binder</term>
<term>Solid particles</term>
<term>Static voltage</term>
<term>Stearic</term>
<term>Stearic acid</term>
<term>Technol</term>
<term>True density</term>
<term>Uncontrollable agglomerate growth</term>
<term>Wider size distribution</term>
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<term>Agglomerate</term>
<term>Agglomerate formation</term>
<term>Agglomerate growth</term>
<term>Agglomerate growth mechanisms</term>
<term>Agglomerate size distribution</term>
<term>Agglomerate strength</term>
<term>Agglomeration</term>
<term>Agglomeration experiments</term>
<term>Agglomeration process</term>
<term>Anhydrous</term>
<term>Anhydrous dicalcium phosphate</term>
<term>Anhydrous lactose</term>
<term>Binder</term>
<term>Binder distribution</term>
<term>Binder viscosity</term>
<term>Breakage</term>
<term>Chem</term>
<term>Coalescence</term>
<term>Corn starch</term>
<term>Deformability</term>
<term>Densification</term>
<term>Distribution mechanism</term>
<term>Droplet</term>
<term>Granule</term>
<term>Granule size</term>
<term>High impeller speed</term>
<term>High shear mixer</term>
<term>High shear mixers</term>
<term>High viscosity</term>
<term>Higher impeller speed</term>
<term>Higher porosity</term>
<term>Higher viscosity</term>
<term>Holm</term>
<term>Immersion mechanism</term>
<term>Impeller</term>
<term>Impeller speed</term>
<term>Intragranular</term>
<term>Intragranular porosity</term>
<term>Kristensen</term>
<term>Lactose</term>
<term>Lactose monohydrate</term>
<term>Liquid saturation</term>
<term>Loose structure</term>
<term>Lower viscosity</term>
<term>Mass ratio</term>
<term>Meltable</term>
<term>Meltable binder</term>
<term>Mixer</term>
<term>Mixer torque rheometer</term>
<term>Molten binder</term>
<term>Monohydrate</term>
<term>Nucleation phase</term>
<term>Other hand</term>
<term>Particle shape</term>
<term>Particle size</term>
<term>Pelletization</term>
<term>Pelletization process</term>
<term>Pharm</term>
<term>Porosity</term>
<term>Powder technol</term>
<term>Powder technology</term>
<term>Primary particles</term>
<term>Resistivity</term>
<term>Saturation</term>
<term>Shearing forces</term>
<term>Size distribution</term>
<term>Small particle size</term>
<term>Solid binder</term>
<term>Solid particles</term>
<term>Static voltage</term>
<term>Stearic</term>
<term>Stearic acid</term>
<term>Technol</term>
<term>True density</term>
<term>Uncontrollable agglomerate growth</term>
<term>Wider size distribution</term>
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<front><div type="abstract" xml:lang="en">Abstract: This paper presents a review of factors affecting the agglomerate formation and growth mechanisms in melt agglomeration in high shear mixers. The agglomerate formation occurs either by distribution or immersion or by a combination of both mechanisms. Distribution is promoted by a low binder viscosity, by a high impeller speed, and by a small binder particle size. Effects of the liquid saturation of the agglomerates, impeller speed, particle properties, binder viscosity, and electrostatic charging on the subsequent agglomerate growth are discussed, and experimental results are presented. The agglomerate growth becomes controlled by the balance between the agglomerate strength and the shearing forces. If the agglomerate strength is sufficiently high to resist the shearing forces of the rotating impeller, the dominant agglomerate growth mechanism will be coalescence. The shearing forces will give rise to breakage if the agglomerate strength is too low, and then agglomerate growth will occur by a simultaneous buildup and breakdown of agglomerates, possibly combined with growth by layering of fragments upon larger agglomerates. Provided that the liquid saturation is sufficiently high, a higher agglomerate strength is primarily caused by a higher binder viscosity, a smaller particle size, an irregular particle shape, and by densification of the agglomerates.</div>
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Growth mechanisms in melt agglomeration in high shear mixers

Growth mechanisms in melt agglomeration in high shear mixers

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri